• Understanding the molecular basis of human heart failure including various forms of genetic cardiomyopathies and atrial fibrillation using omics and imaging techniques
• Deciphering mechanisms of peripartum cardiomyopathy - a rare heart disease that affects pregnant women
• Population based gene association study of cardiac and metabolic co-factors

A/Prof Li is the Co-lead of the Chronic Disease Theme in the Centre of Healthy Futures and Higher Degree Research Director of Health. She holds honorary and adjunct academic positions at University of Sydney and La Trobe University. Her direct research interests cover cardiovascular and musculoskeletal physiology utilising a combination of biophysical, imaging and omics techniques. She combines her extensive pre- and post-doctoral training from internationally leading biophysics and physiology laboratories and her experience in teaching and coordinating human anatomy to build a wholistic understanding of muscle function from molecules to whole organs. She has over a decade of research experience in the area of cardiac muscle biology. Over the years, she has made significant contributions to the understanding of molecular and cellular mechanisms underpinning human cardiovascular health through the process of ageing and disease (see 10.3390/jcdd10050188). She utilised molecular motility assays and single molecule imaging to understand the functional impact of mutations and post-translational modifications in muscle contraction (see 10.1073/pnas.1910549116). Her strong interest in this area has led her to join the board of the Sydney Heart Bank (see 10.1002/ehf2.13768) that has provided researchers all over the world with access to human heart tissue to further the common goal of understanding chronic cardiovascular diseases.

For those interested in adances in cardiovascular research, see A/Prof Li's co-edited e-book in Frontiers in Cardiovascular Medicine (2023): 

https://www.frontiersin.org/research-topics/38473/molecular-and-cellular-mechanisms-of-heart-failure-pathophysiology-pathogenesis-and-therapeutics#overview