Healthcare organizations are facing the challenge of delivering high-quality services through effective process management at all levels- locally, regionally, nationally, and internationally. There have been frequent changes of clinical processes and increased interactions between different functional units. Software agents were adopted to provide the means to accomplish real-time application, due to their autonomous, reactive and/or proactive nature, and their effectiveness in dynamic environments by incorporating coordination strategies. Multi Agent Systems (MAS) will helps in minimizing the waiting time of patient and cost of the care also it can be used to represent the real conditions, courses, and the human decision behavior. This paper presents an overview of health care system, intelligent software agents and integration of both to achieve better Quality of service.