Assessing agreement between point of care and laboratory results for lipid testing from a clinical perspective

Angela Gialamas; Caroline O. Laurence; Lisa N. Yelland; Philip Tideman; Paul Worley; Mark D. Shephard; Rosy Tirimacco; Kristyn J. Willson; Philip Ryan; Janice Gill; David W. Thomas; Justin J. Beilby

doi:10.1016/j.clinbiochem.2009.11.014

Assessing agreement between point of care and laboratory results for lipid testing from a clinical perspective

Angela Gialamas, Caroline O. Laurence, Lisa N. Yelland, Philip Tideman, Paul Worley, Mark D. Shephard, Rosy Tirimacco, Kristyn J. Willson, Philip Ryan, Janice Gill, David W. Thomas, Justin J. Beilby

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Objectives: Investigate agreement between lipid pathology results from point-of-care testing (PoCT) devices and laboratories. Design and methods: Agreement was assessed using the Bland-Altman method. Results: Mean difference (limits of agreement) were: - 0.28 mmol/L (- 1.04, 0.48) for total cholesterol, - 0.09 mmol/L, (- 0.55, 0.36) for HDL-C. Median difference (nonparametric limits of agreement) were 0.07 mmol/L, (- 0.40, 3.04) for triglycerides. Conclusions: The clinical acceptability of the variation between lipid PoCT and laboratory test results is debatable but our work provides baseline data for further research.

Original language	English
Pages (from-to)	515-518
Number of pages	4
Journal	Clinical Biochemistry
Volume	43
Issue number	4-5
DOIs	https://doi.org/10.1016/j.clinbiochem.2009.11.014
Publication status	Published - 1 Mar 2010
Externally published	Yes

Keywords

General practice
Lipids
Point of care testing

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10.1016/j.clinbiochem.2009.11.014

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Gialamas, A., Laurence, C. O., Yelland, L. N., Tideman, P., Worley, P., Shephard, M. D., Tirimacco, R., Willson, K. J., Ryan, P., Gill, J., Thomas, D. W., & Beilby, J. J. (2010). Assessing agreement between point of care and laboratory results for lipid testing from a clinical perspective. Clinical Biochemistry, 43(4-5), 515-518. https://doi.org/10.1016/j.clinbiochem.2009.11.014

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abstract = "Objectives: Investigate agreement between lipid pathology results from point-of-care testing (PoCT) devices and laboratories. Design and methods: Agreement was assessed using the Bland-Altman method. Results: Mean difference (limits of agreement) were: - 0.28 mmol/L (- 1.04, 0.48) for total cholesterol, - 0.09 mmol/L, (- 0.55, 0.36) for HDL-C. Median difference (nonparametric limits of agreement) were 0.07 mmol/L, (- 0.40, 3.04) for triglycerides. Conclusions: The clinical acceptability of the variation between lipid PoCT and laboratory test results is debatable but our work provides baseline data for further research.",

keywords = "General practice, Lipids, Point of care testing",

author = "Angela Gialamas and Laurence, {Caroline O.} and Yelland, {Lisa N.} and Philip Tideman and Paul Worley and Shephard, {Mark D.} and Rosy Tirimacco and Willson, {Kristyn J.} and Philip Ryan and Janice Gill and Thomas, {David W.} and Beilby, {Justin J.}",

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AU - Gialamas, Angela

AU - Laurence, Caroline O.

AU - Yelland, Lisa N.

AU - Tideman, Philip

AU - Worley, Paul

AU - Shephard, Mark D.

AU - Tirimacco, Rosy

AU - Willson, Kristyn J.

AU - Ryan, Philip

AU - Gill, Janice

AU - Thomas, David W.

AU - Beilby, Justin J.

PY - 2010/3/1

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N2 - Objectives: Investigate agreement between lipid pathology results from point-of-care testing (PoCT) devices and laboratories. Design and methods: Agreement was assessed using the Bland-Altman method. Results: Mean difference (limits of agreement) were: - 0.28 mmol/L (- 1.04, 0.48) for total cholesterol, - 0.09 mmol/L, (- 0.55, 0.36) for HDL-C. Median difference (nonparametric limits of agreement) were 0.07 mmol/L, (- 0.40, 3.04) for triglycerides. Conclusions: The clinical acceptability of the variation between lipid PoCT and laboratory test results is debatable but our work provides baseline data for further research.

AB - Objectives: Investigate agreement between lipid pathology results from point-of-care testing (PoCT) devices and laboratories. Design and methods: Agreement was assessed using the Bland-Altman method. Results: Mean difference (limits of agreement) were: - 0.28 mmol/L (- 1.04, 0.48) for total cholesterol, - 0.09 mmol/L, (- 0.55, 0.36) for HDL-C. Median difference (nonparametric limits of agreement) were 0.07 mmol/L, (- 0.40, 3.04) for triglycerides. Conclusions: The clinical acceptability of the variation between lipid PoCT and laboratory test results is debatable but our work provides baseline data for further research.

KW - General practice

KW - Lipids

KW - Point of care testing

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Assessing agreement between point of care and laboratory results for lipid testing from a clinical perspective

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Keywords

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