Dopaminergic behaviour in chicken retina and the effect of form deprivation

P. L. Megaw, I. G. Morgan, M. K. Boelen

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Abstract

Purpose: Dopamine (DA) is considered to be a neurotransmitter involved in light-adaptive responses in the retina and has been implicated in the control of the eye growth induced by form deprivation. Vitreal DOPAC was shown to be a good indicator of retinal dopaminergic activity. Methods/Results: Dopaminergic activity was highest during the light, with vitreal DOPAC levels rising within 3 h of light exposure. Form deprivation attenuated dopaminergic activity, as the rise in vitreal DOPAC levels on light exposure was reduced in form-deprived eyes, compared with control eyes. Conclusion: The lack of sustained activation of DA release may explain the role of DA in the control of eye-growth.

Original languageEnglish
Pages (from-to)S76-S78
JournalAustralian and New Zealand Journal of Ophthalmology
Volume25
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 1 May 1997
Externally publishedYes

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Keywords

  • Amacrine ceils
  • Chicken
  • Dopamine
  • DQPAC
  • Eye-growth
  • Form deprivation

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