Dopaminergic behaviour in chicken retina and the effect of form deprivation

P. L. Megaw; I. G. Morgan; M. K. Boelen

doi:10.1111/j.1442-9071.1997.tb01764.x

Dopaminergic behaviour in chicken retina and the effect of form deprivation

P. L. Megaw, I. G. Morgan, M. K. Boelen

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

Purpose: Dopamine (DA) is considered to be a neurotransmitter involved in light-adaptive responses in the retina and has been implicated in the control of the eye growth induced by form deprivation. Vitreal DOPAC was shown to be a good indicator of retinal dopaminergic activity. Methods/Results: Dopaminergic activity was highest during the light, with vitreal DOPAC levels rising within 3 h of light exposure. Form deprivation attenuated dopaminergic activity, as the rise in vitreal DOPAC levels on light exposure was reduced in form-deprived eyes, compared with control eyes. Conclusion: The lack of sustained activation of DA release may explain the role of DA in the control of eye-growth.

Original language	English
Pages (from-to)	S76-S78
Journal	Australian and New Zealand Journal of Ophthalmology
Volume	25
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1111/j.1442-9071.1997.tb01764.x
Publication status	Published - 1 May 1997
Externally published	Yes

Keywords

Amacrine ceils
Chicken
Dopamine
DQPAC
Eye-growth
Form deprivation

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10.1111/j.1442-9071.1997.tb01764.xLicence: CC BY

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Dopaminergic behaviour in chicken retina and the effect of form deprivation

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