Factors that may mediate the relationship between physical activity and the risk for developing knee osteoarthritis

Donna M. Urquhart, Cathy Soufan, Andrew J. Teichtahl, Anita E. Wluka, Fahad Hanna, Flavia M. Cicuttini

Research output: Contribution to journalReview article

37 Citations (Scopus)


Studies investigating the effect of physical activity on risk for developing osteoarthritis at weight-bearing joints have reported conflicting results. We examine evidence to suggest that this may be due to the existence of subgroups of individuals who differ in their response to physical activity, as well as methodological issues associated with the assessment of knee joint structure and physical activity. Recommendations for future studies of physical activity and the development of knee osteoarthritis are discussed.

Original languageEnglish
Article number203
JournalArthritis Research and Therapy
Issue number1
Publication statusPublished - 4 Feb 2008
Externally publishedYes


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