Glutamine metabolism and optimal immune and CNS function

Philip Newsholme, Vinicius Leonardo Sousa Diniz, Garron Thomas Dodd, Vinicius Cruzat

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)

Abstract

Abbreviations: CNS, Central Nervous System; GSH, glutathione reduced; GSSG, glutathione oxidised; GABA, gamma-Amino butyric acid; HSP, Heat shock protein, NAD+, nicotinamide adenine dinucleotide oxidised; NADPH, nicotinamide adenine dinucleotide phosphate reduced Acknowledgements We thank the Faculty of Health, Torrens University Australia for research support. We also thank the Curtin Medical School and The Curtin Health Innovation Research Institute for research support and provision of excellent research facilities. GTD would also like to acknowledge The University of Melbourne for provision of research facilities. Financial Support Australian Research Council (ARC) Linkage grant LP190100130, National Health and Medical Research Council (NHMRC) of Australia (Grants: 1160043, 2002427), Diabetes Australia Trust (Grant: Y20G-DODG) and the Australian Research Council for research funding (Grant: DP220102132) and the São Paulo Research Foundation (FAPESP), grant #2021/13119-Conflict of interest The authors declare no conflicting or competing interests.

Original languageEnglish
JournalProceedings of the Nutrition Society
DOIs
Publication statusPublished - 2022

Keywords

  • Amino acids
  • Central Nervous System
  • Immune cells
  • Intermediary metabolism

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