This chapter describes the nexus between the underlying scourges of human immunodeficiency virus (HIV)/AIDS in communities such as Soweto and the range of related heart disease presentations. It presents a case study examining the Heart of Soweto registry in order to gain knowledge of the impact of HIV/AIDS on heart disease presentations in a typical African urban community at high risk of exposure to the virus. The study focuses on the potential impact of concurrently prescribed HAART. Pharmacological therapy most commonly comprised loop diuretics in addition to spironolactone, a beta blocker, an ACE inhibitor, aspirin, and digoxin. Immediately following the study period, the South African government initiated a national program of HAART application in those infected with HIV. As noted in the original report, this will have a mitigating effect on presentations of HIV-related CMO and pericardial effusion/pericarditis.
|Title of host publication||Heart of Africa|
|Subtitle of host publication||Clinical Profile of an Evolving Burden of Heart Disease in Africa|
|Number of pages||7|
|Publication status||Published - 13 May 2016|
- African urban community
- Heart disease
- Pharmacological therapy