Management of frailty: opportunities, challenges, and future directions

Elsa Dent, Finbarr C. Martin, Howard Bergman, Jean Woo, Roman Romero-Ortuno, Jeremy D. Walston

Research output: Contribution to journalReview articlepeer-review

741 Citations (Scopus)


Frailty is a complex age-related clinical condition characterised by a decline in physiological capacity across several organ systems, with a resultant increased susceptibility to stressors. Because of the heterogeneity of frailty in clinical presentation, it is important to have effective strategies for the delivery of care that range across the continuum of frailty severity. In clinical practice, we should do what works, starting with frailty screening, case identification, and management of frailty. This process is unarguably difficult given the absence of an adequate evidence base for individual and health-system interventions to manage frailty. We advocate change towards individually tailored interventions that preserve an individual's independence, physical function, and cognition. This change can be addressed by promoting the recognition of frailty, furthering advancements in evidence-based treatment options, and identifying cost-effective care delivery strategies.

Original languageEnglish
Pages (from-to)1376-1386
Number of pages11
JournalThe Lancet
Issue number10206
Publication statusPublished - 12 Oct 2019


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