Patellofemoral and tibiofemoral articular cartilage and subchondral bone health following arthroscopic partial medial meniscectomy

Yuanyuan Wang, Alasdair R. Dempsey, David G. Lloyd, Peter M. Mills, Tim Wrigley, Kim L. Bennell, Ben Metcalf, Fahad Hanna, Flavia M. Cicuttini

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)


Purpose: To examine articular cartilage and subchondral bone changes in tibiofemoral and patellofemoral joints following partial medial meniscectomy. Methods: For this cross-sectional study, 158 patients aged 30-55 years, without evidence of knee osteoarthritis at arthroscopic partial medial meniscectomy (APMM), and 38 controls were recruited. MRI was performed once on the operated knee for each subcohort of 3 months, 2 or 4 years post-surgery, and the randomly assigned knee of the controls. Cartilage volume, cartilage defects, and bone size were assessed using validated methods. Results: Compared with controls, APMM patients had more prevalent cartilage defects in medial tibiofemoral (OR = 3.17, 95%CI 1.24-8.11) and patellofemoral (OR = 13.76, 95%CI 1.52-124.80) compartments, and increased medial tibial plateau bone area (B = 143.8, 95%CI 57.4-230.2). Time from APMM was positively associated with cartilage defect prevalence in medial tibiofemoral (OR = 1.02, 95%CI 1.00-1.03) and patellofemoral (OR = 1.04, 95%CI 1.01-1.07) compartments, and medial tibial plateau area (B = 2.5, 95%CI 0.8-4.3), but negatively associated with lateral tibial cartilage volume (B = -4.9, 95%CI -8.4 to -1.5). The association of APMM and time from APMM with patellar cartilage defects was independent of tibial cartilage volume. Conclusions: Partial medial meniscectomy is associated with adverse effects on articular cartilage and subchondral bone, which are associated with subsequent osteoarthritis, in both tibiofemoral and patellofemoral compartments. Level of evidence: III.

Original languageEnglish
Pages (from-to)970-978
Number of pages9
JournalKnee Surgery, Sports Traumatology, Arthroscopy
Issue number5
Publication statusPublished - 1 May 2012
Externally publishedYes


  • Cartilage
  • Magnetic resonance imaging
  • Meniscectomy
  • Osteoarthritis
  • Subchondral bone


Dive into the research topics of 'Patellofemoral and tibiofemoral articular cartilage and subchondral bone health following arthroscopic partial medial meniscectomy'. Together they form a unique fingerprint.

Cite this