Rheumatic Heart Disease

Simon Stewart, Melinda Jane Carrington, Karen Sliwa

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Citations (Scopus)


Rheumatic heart disease (RHD) with its close link to childhood poverty and heavy exposure to communicable diseases represents one of the truly reliable barometers of the socioeconomic wealth of a population and country, particularly in the setting of limited access to even basic preventive health care measures. Using systematic clinical profiling of the Heart of Soweto Study cohort to investigate de novo presentations of heart disease, with a careful examination and classification of all cases of valvular disease and dysfunction via echocardiography, this study focused on the probable incidence and clinical characteristics of RHD in the Sowetan community. Primary VHD plays a vital role in the development of HF in the sub-Saharan African context. Quite apart from a unique report on late-stage RHD, this pivotal study uncovered a significant component of valve disease and dysfunction as part of late presentations of heart disease in Soweto.

Original languageEnglish
Title of host publicationHeart of Africa
Subtitle of host publicationClinical Profile of an Evolving Burden of Heart Disease in Africa
Number of pages15
ISBN (Electronic)9781118336960
ISBN (Print)9781119097136
Publication statusPublished - 13 May 2016
Externally publishedYes


  • Acute rheumatic fever
  • Childhood poverty
  • Communicable diseases
  • Rheumatic heart disease
  • Valvular disease


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