Toward the recognition and management of sarcopenia in routine clinical care

Elsa Dent, Jean Woo, David Scott, Emiel O. Hoogendijk

Research output: Contribution to journalArticlepeer-review


Sarcopenia, the age-associated decline in skeletal muscle mass and function, is a major cause of functional decline and mortality in older adults. Despite its importance, sarcopenia often remains unrecognized and inadequately managed in routine clinical care. A major hinderance to its clinical integration is the variation in diagnostic tools for sarcopenia. Diagnostic tools include those of the European Working Group on Sarcopenia in Older People (versions 1 and 2), those of the Asian Working Group for Sarcopenia (versions 1 and 2), and that of the Sarcopenia Definition and Outcomes Consortium. The management decision process of sarcopenia warrants an evaluation of risk factors such as a sedentary lifestyle, inadequate exercise, poor nutritional intake, smoking, depression and living circumstances. Herein, we provide an evidence-based update of the prevention and management of sarcopenia and propose practical information to facilitate the disease’s adoption into routine care.
Original languageEnglish
Pages (from-to)982-990
Number of pages9
JournalNature Aging
Issue number11
Publication statusPublished - 2021


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