BACKGROUND: In a rapidly evolving digital world, it is crucial that general practice embraces the potential of artificial intelligence (AI) and virtual reality (VR) in a real and proactive manner. OBJECTIVE: Using examples of AI and VR, the article outlines some of the benefits and challenges we face in integrating these digital tools into daily clinical practice and our training programs. DISCUSSION: It is clear that AI and VR digital innovations will continue to grow in significance, with more and more options being offered to clinicians. As we increase our understanding of the benefits of these technologies, adapting our traditional curricula and daily clinical practice will require an openness to change. This is somewhat easier with VR, as it is a low-risk intervention that is providing an additional clinical intervention modality. AI is generating more challenges that will require a balanced, ongoing discussion involving clinicians and AI practitioners.